Basic Metabolic Panel (Calcium, ionized) (Glucose Random, Creatinine, Urea, Calcium ionized, Bicarbonate, Sodium, Potassium, Chloride)

In situations where the total calcium is normal but does not fit the clinical picture, e.g., hyperparathyroidism, a determination of the ionized calcium will, many times, show an elevation in the “bioavailable” calcium component. This may be due to alterations in protein concentrations, especially albumin, that binds most of the calcium in the circulation.