SS-A (Ro) & SS-B (La) IgG Antibodies

SS-A (Ro) & SS-B (La) are extractable nuclear antigens. SS-ARo antibodies occur in patients with Sjogren’s syndrome (90%), Lupus erythematosus (40-60%) & Rheumatoid arthritis. SS-BLa antibodies occur m patients with Sjogren’s syndrome (60%) & Lupus erythematosus (15%). This assay is useful for evaluating patients with signs and symptoms of connective tissue disorder m whom ANA is positive.