25 Jul
Urinary citrate is a major inhibitor of kidney stone formation due to it binding of calcium in urine.
Condition like that metabolic acidosis, increased acid ingestion, hypokalemia, and hypomagnesemia lowers renal tubular pH or intracellular pH, thus decreasing urinary citrate. This assay is used for diagnosing risk factors for patients with calcium kidney stones, and for monitoring
results of therapy in patients with calcium stones or renal tubular acidosis.