01 Oct
Glutamic Acid Decarboxylase (GAD-65) Antibody is useful to diagnose insulin dependent diabetes mellitus (IDDM, Type I diabetes), to assess risk for development of IDDM, to predict onset of IDDM, and risk of development of related endocrine disorders, e.g., thyroiditis. Before clinical onset, Type I diabetes is characterized by lymphocytic infiltration of the islet cells, and by circulating autoantibodies against a variety of islet cell antigens including GAD-65, IA-2 (a tyrosine phosphatase-like protein), and insulin autoantibody (IAA).