25 Jul
Histoplasma capsulatum causes disease that is usually self-limited, affects the lungs, and is asymptomatic. It can also cause chronic cavitary pulmonary disease, disseminated disease, and meningitis may occur which can be fatal, especially in young children and in immunosuppressed patients. Patients infected with Histoplasma capsulatum demonstrate a serum antibody with a rising titer within 6 weeks of infection. A rising titer is associated with progressive infection.
Specific antibody may persists for a few weeks to a year.