25 Jul
LDL cholesterol is a key factor in the pathogenesis of atherosclerosis and coronary artery disease (CAD), while HDL cholesterol
has often been observed to have a protective effect. Even within the normal range of total cholesterol concentrations, an increase in LDL cholesterol can be associated with increased risk for CAD. LDL cholesterol binds to receptor sites on macrophages in blood vessel walls inciting several changes in the blood wall which enhance atherosclerotic plaque
development.