MEFV Gene Mutation (Mediterranean Fever) Detection

Familial Mediterranean fever (FMF) is a hereditary auto-inflammatory disease which is most prevalent in Mediterranean populations. It is characterized by recurrent febrile episodes with abdominal pain, pleuritis, arthritis, and, sometimes, pericarditis and meningitis. FMF is caused
by mutations in the MEFV gene encoding pyrin. FMF is typically inherited as an autosomal recessive condition, but heterozygous mutation carriers may also develop symptoms. This assay aids in confirmation of FMF.