25 Jul
Widely used clinical application of NT-proBNP testing is for the emergent diagnosis of CHF in patients presenting with acute dyspnea. Nevertheless, elevated NPs levels can be found in many conditions involving left ventricular dysfunction/ hypertrophy, right ventricular dysfunction secondary to pulmonary diseases, cardiac inflammatory/ infectious diseases, endocrine diseases
and high output status without decreased LV ejection fraction. Even in the absence of significant volume overload or LV dysfunction, markedly elevated proBNP levels can be found in patients with multiple comorbidities.