Thalassemia, Beta, Line Probe Assay

This assay is used, as a follow up testing to an abnormal hemoglobin HPLC/ electrophoresis, for elucidating beta thalassemia genotypes. Amplified DNA from the beta thalassemia patient samples are probed for Mutations using a line probe assay.Beta thalassemia specific wild type genes and mutant genes are detected using an Amplification refractory mutation system
(ARMS) PCR.