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JAK 2 Exon 12 Mutation Detection

Test Code: 16000 CPT Code:
Specimen Type: EDTA whole blood/ EDTA bone marrow
Sample Volume: 5.0 mL (3.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Grosshemolysis. Moderately to severely clotted.
Methodology: PCR-Sequencing
Special Requirements: Specimen must arrive within 5 days (120 hours) of collection. Date of collection is required.
Clinical Significance:

This assay aids in distinction between a reactive cytosis and a myeloproliferative neoplasm, particularly when a diagnosis of polycythemia is being entertained.

Run Day: Fri
Reporting Day: 9th day

JAK2 V617F Mutation Detection, Blood

Test Code: 8415 CPT Code: 81270
Specimen Type: Whole Blood EDTA (lavender top)/ EDTA bone marrow
Sample Volume: 3 mL
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Grosshemolysis. Moderately to severely clotted
Methodology: Real Time PCR
Special Requirements: Clinical details are required
Clinical Significance:

The Janus kinase 2 gene (JAK2) codes for a tyrosine kinase (JAK2) that is associated with the cytoplasmic portion of atype of transmembrane cytokine and growth factor receptors important for signal transduction. BCR-ABL1-negative myeloproliferative neoplasms commonly harbor an acquired single nucleotide mutation in JAK2 characterized as V617F. JAK2 V617F is present in 95% to 98% of polycythemia vera, 50% to 60% of primary myelofibrosis, and 50% to 60% of essential thrombocythemia.

Run Day: Mon, Wed, Fri
Reporting Day: 4th day

Jaw Resection for Tumor, Mandibulectomy

Test Code: 1422 CPT Code: 88309
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Jaw Resection for Tumor, Maxillectomy

Test Code: 1423 CPT Code: 88309
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day