JAK 2 Exon 12 Mutation Detection
Test Code: 16000 |
CPT Code: |
Specimen Type: EDTA whole blood/ EDTA bone marrow |
Sample Volume: 5.0 mL (3.0mL - min) |
Transport Condition: Refrigerated condition |
Specimen Rejection Criteria: Grosshemolysis. Moderately to severely clotted. |
Methodology: PCR-Sequencing |
Special Requirements: Specimen must arrive within 5 days (120 hours) of collection. Date of collection is required. |
Clinical Significance: This assay aids in distinction between a reactive cytosis and a myeloproliferative neoplasm, particularly when a diagnosis of polycythemia is being entertained.
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Run Day: Fri |
Reporting Day: 9th day |
JAK2 V617F Mutation Detection, Blood
Test Code: 8415 |
CPT Code: 81270 |
Specimen Type: Whole Blood EDTA (lavender top)/ EDTA bone marrow |
Sample Volume: 3 mL |
Transport Condition: Refrigerated condition |
Specimen Rejection Criteria: Grosshemolysis. Moderately to severely clotted |
Methodology: Real Time PCR |
Special Requirements: Clinical details are required |
Clinical Significance: The Janus kinase 2 gene (JAK2) codes for a tyrosine kinase (JAK2) that is associated with the cytoplasmic portion of atype of transmembrane cytokine and growth factor receptors important for signal transduction. BCR-ABL1-negative myeloproliferative neoplasms commonly harbor an acquired single nucleotide mutation in JAK2 characterized as V617F. JAK2 V617F is present in 95% to 98% of polycythemia vera, 50% to 60% of primary myelofibrosis, and 50% to 60% of essential thrombocythemia.
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Run Day: Mon, Wed, Fri |
Reporting Day: 4th day |
Jaw Resection for Tumor, Mandibulectomy
Test Code: 1422 |
CPT Code: 88309 |
Specimen Type: Tissue |
Sample Volume: Specimen in 10% buffered formalin |
Transport Condition: Room temperature |
Specimen Rejection Criteria: Received frozen |
Methodology: Microscopy |
Special Requirements: Clinical history and sample site are essential |
Clinical Significance: The nature of possible underlying disease can be ruled out/confirmed through histopathological examination
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Run Day: Daily, except Fri |
Reporting Day: 4th day |
Jaw Resection for Tumor, Maxillectomy
Test Code: 1423 |
CPT Code: 88309 |
Specimen Type: Tissue |
Sample Volume: Specimen in 10% buffered formalin |
Transport Condition: Room temperature |
Specimen Rejection Criteria: Received frozen |
Methodology: Microscopy |
Special Requirements: Clinical history and sample site are essential |
Clinical Significance: The nature of possible underlying disease can be ruled out/confirmed through histopathological examination
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Run Day: Daily, except Fri |
Reporting Day: 4th day |