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Salicylates are used in the treatment of fever, analgesia and in the treatment of acute rheumatic fever, rheumatoid arthritis and for inhibition of platelet aggregation in patients with CAD. When treating rheumatoid arthritis, salicylates reduce the inflammation in joint tissues. Salicylate levels are monitored to assess toxicity.

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Typhoid fever is a life threatening illness caused by the bacterium Salmonella typhi, in which an early diagnosis is highly desirable. The diagnosis of typhoid consists of isolation of the bacilli and the demonstration of antibodies.
The isolation of the bacilli is time consuming. Typhi Check can be a valuable tool in diagnosis
of acute stage in typhoid fever. It is a qualitative test for the detection of IgM antibodies to S. typhi in human serum, plas-
ma, or whole blood. It should, however, be used as a screening test in clinically suspected cases only, and its results should be confirmed by other supplemental method before taking clinical decisions.

Scl 70 (topoisomerase 1) is a nucleolar enzyme. Scl 70 antibodies are considered to be specific for scleroderma (systemic sclerosis) and are found in up to 60% of these patients. Scl 70 antibodies are more common in patients with extensive skin involvement and interstitial pulmonary fibrosis, and are considered a poor prognostic sign.

Scrub Typhus is an infectious disease caused by Orientia tsutsugamushi (formerly Rickettsia), belonging to the family Rickettsiaceae. It is transmitted by bite from the larval trombiculid mite. Early diagnosis of acute scrub typhus infection is important not only for patient management, but also for the prevention of complications. This assay aids in diagnosis of acute scrub typhus.

Selenium is an essential element and is a cofactor necessary for activity of glutathione peroxidase (GSH-Px). The absence of selenium correlates with loss of GSH-Px activity and is associated with damage to cell membranes due to accumulation of free radicals.
This assay is useful for monitoring selenium replacement therapy.

Test is used for evaluation of infertility cases.

Fructose is the energy source for sperm motility. A positive fructose is considered normal. Azoospermia and fructose negative results may indicate an absence of seminal vesicles/ vas deferens in the area of seminal vesicles.

Serotonin concentrations are greatly increased in patients with carcinoid syndrome. Carcinoid tumors are associated with multiple endocrine neoplasia (MEN) types I and II. These tumors are associated with flushing, diarrhea, pain, and other symptoms.

The hormones testosterone, dihydrotestosterone and estrogens are bound to SHBG. SHBG concentrations are increased in pregnancy, birth control pills usage, and decreased in obesity. Changes in SHBG will influence the total hormone concentration but not the free hormone concentrations.

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Fungal infections are more common in immunocompromised patients. Direct examination provide an immediate early presumptive diagnosis and enables initiation of antifungal therapy.

For pathogen detection / MRSA screening

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Sm is a small nuclear ribonucleoprotein composed of several protein autoantigens designated B, B1, D, E, F, and G. Sm Antibodies are highly specific for systemic lupus erythematosus (SLE) and occur in approximately 30% of SLE patients. This assay aids in diagnosis of SLE.

The excretion of sodium varies with dietary intake. There is a diurnal variation of sodium excretion with excretion being greater during daytime than during the night. Decreased levels are seen in congestive heart failure, excessive sweating, diarrhea, pyloric obstruction, malabsorption and primary aldosteronism. Increased levels may be due to increased salt intake, failure of the adrenal glands, diabetic acidosis, salt losing renal disease, diuretic therapy and water deprivation dehydration. The creatinine value provides evidence of proper 24 hour urine collection.

The excretion of sodium varies with dietary intake. There is a diurnal variation of sodium excretion with excretion being greater during daytime than during the night. Decreased levels are seen in congestive heart failure, excessive sweating, diarrhea, pyloric obstruction, malabsorption and primary aldosteronism. Increased levels may due to increased salt intake, failure of the adrenal glands, diabetic acidosis, salt losing renal disease, diuretic therapy and water deprivation dehydration. The creatinine value provides evidence of proper 24 hour collection

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Anti-soluble liver antigen antibodies are detected in 10-30% of patients with type 1 autoimmune hepatitis (AIH). It is not detect-
ed in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis. This antibody is directed against a
UGA suppressor tRNA associated protein. In certain AIH patients, this antibody may be the only autoantibody detected by currently available assays.

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The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

For detection of malignant/ inflammatory/ infectious conditions

C. trachomatis, N. gonorrhoeae, M. gnitalium, Trichomonas vaginalis, Mycoplasma hominis, Ureaplasma urealyticum, Ureaplasma parvum, HSV 1 , HSV 2 and Treponema pallidum are most common pathogens causing STDs. This panel is used for rapid detection of DNA
of these pathogens in clinical specimens by Multiplex RT PCR, therby aiding in the diagnosis of STDs caused by them.

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination. Giemsa stain can aid in the detection of H. pylori.

For parasite and occult blood detection

For detection of parasites and pus cells.

This rapid antigen testing to detect group A streptococcal (GAS) infection provides important information for the antibiotic decision making for patients presenting with acute pharyngitis.The Infectious Diseases Society of America (IDSA) guideline on streptococcal pharyngitis
recommends using a rapid test in patients with a modest probability of GAS infection, treating those with a positive rapid test and withholding antibiotics in rapid test negative patients. The guideline recommends culturing rapid test negative children and treating them in case cultures are positive.