17 Hydroxy Progesterone
Test Code: 478 |
CPT Code: 83498 |
Specimen Type: Serum (yellow-top tube) |
Sample Volume: 3.0 mL (1.0mL - min) |
Transport Condition: Refrigerated/ frozen condition |
Specimen Rejection Criteria: Gross hemolysis |
Methodology: Immunoassay |
Special Requirements: Age & Gender for the patient is mandatory |
Clinical Significance: Serum 17-alpha-OHP is characteristically elevated in those cases of congenital adrenal hyperplasia which are due to
21or 11-hydroxylase deficiency. The block in the glucocorticoid pathway results in an accumulation of 17-alpha-OHP and an inhibition of cortisol formation. Adrenocorticotrophin (ACTH) production increases in response to the cortisol deficiency, which in turn, enhances the formation of adrenal androgens.
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Run Day: Mon, Thurs |
Reporting Day: Same day |
25-OH Vitamin D3 & D2, HPLC analysis
Test Code: 6930 |
CPT Code: 82306 |
Specimen Type: Serum collected in a yellow-top tube |
Sample Volume: 3.0 mL (1.0mL - min) |
Transport Condition: Room temperature |
Specimen Rejection Criteria: Gross hemolysis, gross lipemia |
Methodology: HPLC |
Special Requirements: No special precautions needed |
Clinical Significance: This assay should be used to monitor patients taking vitamin D supplements as well as to diagnose vitamin D deficiency. This assay employs liquid chromatography tandem mass spectrometry to independently measure and report the two common forms of 25-OHD: 25-OHD3 the endogenous form of the vitamin; and 25-OHD2 the analog form used to treat 25-OHD3 deficiency.
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Run Day: Daily |
Reporting Day: Same day |
5Hydroxyindoleacetic Acid(5-HIAA), 24 Hour,
Urine
Test Code: 13210 |
CPT Code: 83497 |
Specimen Type: 24 hrs urine |
Sample Volume: 20 mL |
Transport Condition: Frozen Strictly |
Specimen Rejection Criteria: Non frozen specimen. Not protected from light. Improper preservative |
Methodology: Enzyme immunoassay |
Special Requirements: Following instructions must be strictly followed: 24 hrs urine to be collected in 15 mL of 6N HCL. While collecting specimen, the container should be kept in dark throughout the collection. To avoid exposure to light, the 20 mL aliquot from the collected 24 hrs urine sample must be wrapped in aluminum foil. Do not consume bananas, pineapple, and nuts 48 hrs prior to the collection of the specimen. Mention clinical details (CT scan, USG & medication) of the patient on the request form. |
Clinical Significance: 5-Hydroxyindoleacetic acid (5HIAA) is the major metabolite of serotonin and is excreted in the urine. Intestinal carcinoid tumors and neuroendocrine tumors
can produce high amounts of 5-HIAA and serotonin, especially in patients with carcinoid syndrome. Assay of 5-HIAA in a 24-hour urine specimen can aid in diagnosis of carcinoid disease
with a high specificity.
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Run Day: Tue |
Reporting Day: Next day |