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Magnesium, 24 Hrs, Urine

Test Code: 16322 CPT Code: 83735
Specimen Type: 24 hrs Urine
Sample Volume: 5 mL
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: NA
Methodology: Spectrophotometry
Special Requirements: 24 hrs urine with 24 mL 6 N HCL. Refrigerate specimen within 4 hours of completion of 24-hour collection. Mention 24 hrs urine volume.
Clinical Significance:

Magnesium, along with potassium, is a major intracellular cation.Renal handling of magnesium is effected by the combination of filtration and reabsorption.
Causes of renal magnesium wasting include endocrine disorders (hyperaldosteronism, hyperparathyroidism), congenital defects (Barter, Gitelman syndromes), exposure to drugs (diuretics,
cis-platinum, aminoglycoside antibiotics, calcineurin inhibitors). 24 hrs urinary magnesium is useful in assessing the cause of abnormal serum magnesium concentrations, determining adequacy of nutritional magnesium, computing urinary calcium oxalate and calcium phosphate supersaturation, and assessing kidney stone risk.

Run Day: Daily
Reporting Day: Same day

Magnesium, Random, Urine

Test Code: 1246 CPT Code: 83735
Specimen Type: Urine in sterile leak proof container
Sample Volume: 10 mL
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: NA
Methodology: Spectrophotometry
Special Requirements: No special precautions needed
Clinical Significance:

Urinary magnesium concentration often decline before serum concentration. Adverse effects, such as arrhythmias, can be observed while serum concentrations are within range.

Run Day: Daily
Reporting Day: Same day

Malaria Antibodies, Serum

Test Code: 371 CPT Code: 86750
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: ECLIA
Special Requirements: No special precautions needed
Clinical Significance:

Malaria is a protozoan parasitic infection, prevalent in subtropical and tropical parts of the world. The test may be helpful in evaluation of tropical spenomegaly. This test is not to be used in lieu of conventional smear diagnosis.

Run Day: Daily
Reporting Day: Same day

Malarial Antigen, Blood

Test Code: 3618 CPT Code: 87899
Specimen Type: Whole blood in lavender-top (EDTA) tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Clot/ gross hemolysis
Methodology: Chromatography
Special Requirements: No special precautions needed
Clinical Significance:

Malaria is a protozoan parasitic infection, prevalent in subtropical and tropical parts of the world. This test is not to be used in lieu of conventional smear diagnosis. Occasionally, test may show negativity even in presence of smear positivity.

Run Day: Daily
Reporting Day: Same day

Malarial Parasites on PBF

Test Code: 453 CPT Code: 87207
Specimen Type: Whole blood in a lavender-top (EDTA) tube
Sample Volume: 3.0 mL (1.0mL min)
Transport Condition: Room temperature
Specimen Rejection Criteria: Hemolysis and clotted
Methodology: Staining/Microscopic
Special Requirements: No special precautions needed
Clinical Significance:

The identification of malarial parasites on peripheral blood smear used for diagnosis, treatment and prognosis.

Run Day: Daily
Reporting Day: Same day

Male Infertility Profile (FSH, LH, Prolactin, Estradiol, Testosterone, Semen Analysis)

Test Code: 3360 CPT Code: Use individual CPTCodes
Specimen Type: Serum collected in a red-top tube, semen sample (collected complete in a clean container , should reach lab within 30 min)
Sample Volume: 3.0 mL (1.0 mL - min)
Transport Condition: Room temperature
Specimen Rejection Criteria: Gross hemolysis
Methodology: GC/MS
Special Requirements: Clinical history is essential. 3 days of abstinence is mandatory. Sample should ready the laboratory within 30 mins of collection
Clinical Significance:

Investigation for infertility.

Run Day: Daily, Testoster- one - Sun, Wed
Reporting Day: Next day

MEFV Gene Mutation (Mediterranean Fever) Detection

Test Code: 16030 CPT Code: 81404
Specimen Type: Whole blood EDTA (lavender-top)
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Nil
Methodology: PCR, DNA sequencing
Special Requirements: Specimen preferred to arrive within 96 hours of draw. Clinical history required.
Clinical Significance:

Familial Mediterranean fever (FMF) is a hereditary auto-inflammatory disease which is most prevalent in Mediterranean populations. It is characterized by recurrent febrile episodes with abdominal pain, pleuritis, arthritis, and, sometimes, pericarditis and meningitis. FMF is caused
by mutations in the MEFV gene encoding pyrin. FMF is typically inherited as an autosomal recessive condition, but heterozygous mutation carriers may also develop symptoms. This assay aids in confirmation of FMF.

Run Day: Daily
Reporting Day: 35th day

Mercury, Quantitative, Serum

Test Code: 4731 CPT Code: 83825
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: Inductively Coupled Plasma Mass Spectrometry (ICPMS)
Special Requirements: No special precautions needed
Clinical Significance:

The primary clinical utility of blood mercury is the determination of abnormal exposures seen at levels over 20 mcg/L. Mercury is absorbed via the respiratory tract (mercury vapors), skin, and gastrointestinal tract. Mercury poisoning can cause kidney damage. The chronic effect of mercury poisoning includes inflammation of mouth and gums, loosening of the teeth, kidney damage, nervousness, depression and spasms.

Run Day: Daily
Reporting Day: 10th day

Metanephrines, 24 Hrs, Urine

Test Code: 16059 CPT Code: 83835
Specimen Type: 24 hrs Urine
Sample Volume: 20 mL
Transport Condition: Frozen condition
Specimen Rejection Criteria: NA
Methodology: Competitive ELISA
Special Requirements: 24 hrs urine (Preservative: 15 20 mL 6N HCL). Should not consume banana, pineapple, chocolates, coffee, ice-creams, diet high in cereals, vanilla, potatoes, B-Complex and other vitamins 48 hrs prior to the collection of the specimen.Discontinue alpha methyldopa, MAO & COMT inhibitors and anti hypertensives at least 72 hrs prior to specimen collection. Medication if taken, should be strictly on the advice of referring physician, and should be mentioned. Freeze the specimen immediately after collection. Clinical details, CT scan, USG findings & medication history required. Mention 24 hrs urine volume.
Clinical Significance:

The 24-hour urinary metanephrines may be used as the first test for low suspicion cases of catecholamine-secreting pheochromocytomas and paragangliomas and also as a confirmatory study in patients with a less than 2-fold elevation in plasma free metanephrines. It can be also used to confirm positive plasma metanephrine results.

Run Day: Tue
Reporting Day: Next day

Methamphetamine, Urine

Test Code: 9824 CPT Code: 80324
Specimen Type: Urine
Sample Volume: 10 mL
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Nil
Methodology: Flowchromatographic Immunoassay
Special Requirements: Collect a random urine specimen.No preservative.
Clinical Significance:

Amphetamines are sympathomimetic amines that stimulate the central nervous system activity. Methamphetamine is a prescription drugs for weight loss, and because of its stimulant effects, it may be abused. This assay is useful for confirming drug exposure.

Run Day: Daily
Reporting Day: 3rd day

Methylmalonic Acid (MMA), Quantitative, Urine

Test Code: 13734 CPT Code: 83921
Specimen Type: Random urine
Sample Volume: 20 mL (10mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Nil
Methodology: Biochemistry
Special Requirements: Overnight fast required. Collect second-voided specimen after an overnight fast.
Clinical Significance:

Elevated levels of methylmalonic acid (MMA) result from inherited defects of enzymes involved
in MMA metabolism or inherited or acquired deficiencies of vitamin B12 or its downstream metabolites. This assay is used for evaluating children with signs and symptoms of methylmalonic academia, and for evaluating individuals with signs and symptoms associated with a variety of causes of cobalamin deficiency.

Run Day: Daily
Reporting Day: 6th day

Microalbuminuria, 24 hr Urine/ Timed Collection

Test Code: 1229 CPT Code: 82043
Specimen Type: Urine in sterile leak proof container
Sample Volume: 10 mL
Transport Condition: Room temperature
Specimen Rejection Criteria: NA
Methodology: Immunoturbidometry
Special Requirements: 24 hrs urine with 10 mL 6 N HCL
Clinical Significance:

Microalbuminuria is defined as levels of albumin ranging from 30 to 300 mg in a 24 hr urine collection. Microalbuminuria is a well known predictor of poor renal outcomes in patients with type 2 diabetes and in essential hypertension. Microalbuminuria has also been shown more recently to be a predictor of cardiovascular outcomes in these populations. There is emerging data that reduction of albuminuria leads to reduced risk of adverse renal and cardiovascular events.

Run Day: Daily
Reporting Day: Same day

Microfilaria Detection, Peripheral Blood

Test Code: 454 CPT Code: 87210
Specimen Type: Whole blood in a lavender-top (EDTA) tube
Sample Volume: 3.0 mL (1.0mL min)
Transport Condition: Room temperature
Specimen Rejection Criteria: NA
Methodology: Microscopy
Special Requirements: No special precautions needed
Clinical Significance:

Filariasis is a disease resulting from parasitization by thread like or filiform worms called filariae. The embryos circulate in lymphatic tissues and blood as microfilaria leading to lymphan-
gitis, lymphadenitis, elephantiasis and tropical eosinophilia.

Run Day: Daily
Reporting Day: Next day

MRSA Culture Screening

Test Code: 6948 CPT Code: 87081
Specimen Type: Nasal Swab/ other swabs from wound site, skin swab
Sample Volume: 1 or 2 swabs
Transport Condition: Room temperature. In case of delay for >2 hours, place in a transportmedium for 24 hours at room temperature.
Specimen Rejection Criteria: Inappropriate specimen transport device, mislabeled specimen, unlabeled specimen, specimen received after prolonged delay (usually more than 24 hours), Specimen received in expired transport medium.
Methodology: Culture & Sensitivity
Special Requirements: Not Applicable
Clinical Significance:

Methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization among inpatients is a well-established risk factor. Additional screening for MRSA needs to be performed, not only to establish the size of the problem and to allow initiation of decolonization measures to prevent the onset of clinical disease, but also to allow implementation of infection control measures that will
be necessary to control the epidemic.

Run Day: Daily
Reporting Day: 4th day

Mumps Antibodies, IgG & IgM, Serum

Test Code: 6169 CPT Code: 86735
Specimen Type: Serum (yellow-top tube)
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition/frozen temperature
Specimen Rejection Criteria: Gross hemolysis
Methodology: Immunoassay
Special Requirements: No special precautions needed
Clinical Significance:

For the diagnosis of mumps virus infection.

Run Day: Sat, Tue, Thurs
Reporting Day: Same day

Mumps Antibodies, IgG, Serum

Test Code: 6170 CPT Code: 86735
Specimen Type: Serum (yellow-top tube)
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition/frozen temperature
Specimen Rejection Criteria: Gross hemolysis, hyperlipemia
Methodology: Immunoassay
Special Requirements: No special precautions needed
Clinical Significance:

Mumps is an acute, usually self-limited systemic illness
characterized by paroditis, high fever and fatigue. One third of infections are asymptomatic. A live attenuated vaccine is available. The mumps EIA IgG Antibodies test is sufficiently sensitive to establish immune status of the patient.

Run Day: Sat, Tue, Thurs
Reporting Day: Same day

Mumps Antibodies, IgM, Serum

Test Code: 6167 CPT Code: 86735
Specimen Type: Serum (yellow-top tube)
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition/frozen temperature
Specimen Rejection Criteria: Gross hemolysis, hyperlipemia
Methodology: Immunoassay
Special Requirements: No special precautions needed
Clinical Significance:

Clinical use is for detection of IgM antibodies to mumps virus

Run Day: Sat, Tue, Thurs
Reporting Day: Same day

Mycobacterium Speciation, Molecular

Test Code: 13863 CPT Code: 87150
Specimen Type: Culture/ sputum/ BAL/ pus
Sample Volume: 5.0 mL (3.0mL - min)
Transport Condition: Room temperature
Specimen Rejection Criteria: Specimens of patients with AFB smear less than 1+ are not acceptable
Methodology: PCR Sequencing
Special Requirements: Clinical history. Specimen source is required
Clinical Significance:

Tuberculosis remains a global pandemic. The increased prevalence and mortality of TB warrants an urgent call to enhance rapid diagnosis. This molecular assay not only allows for a rapid and accurate identification of mycobacteria in a variety of specimens, but also enables precise speciation of Mycobacterium tuberculosis complex (MTB) and its differentiation from non-tuberculous mycobacterium (NTM).

Run Day: Mon
Reporting Day: 5th day

Mycobacterium Tuberculosis Complex, Culture

Test Code: 3619 CPT Code: 87116
Specimen Type: Sputum/ BAL/ urine/ FNAC/ ascitic / pleural / CSF fluids/ tissue in sterile normal saline / bone marrow-EDTA/ paraffin block (Swabs and blood specimen not accepted)
Sample Volume: 3.0 mL (2.0) mL / 1
Transport Condition: Room temperature
Specimen Rejection Criteria: Insufficient quantity of specimen, unlabeled or mislabeled specimen, leaky containers and contaminated specimens
Methodology: Culture
Special Requirements: No special precautions needed
Clinical Significance:

Tuberculosis (TB) is caused by one of several mycobacterial species that belong to the Mycobacterium tuberculosis complex. The human pathogens
are M. tuberculosis, M. africanum, and M. bovis. The other member of the complex, M. microti, is a rodent pathogen. Tuberculosis can develop through progression of recently acquired infection (primary disease), reactivation
of latent infection, or exogenous reinfection.

Run Day: Daily
Reporting Day: 4 Weeks

Mycoplasma Hominis, Culture & Sensitivity

Test Code: 9951 CPT Code: 87109
Specimen Type: Urethral, vaginal, cervical swabs (dry or with media acceptable but preferred with media)/ semen in sterile leak proof container
Sample Volume: 1 or 2swabs/ 2 mL
Transport Condition: Room temperature/ Refrigerated
Specimen Rejection Criteria: Inappropriate specimen transport device, mislabeled specimen, unlabeled specimen
Methodology: Culture & Sensitivity
Special Requirements: Not Applicable
Clinical Significance:

Mycoplasma hominis are frequently isolated from the cervical and vaginal tracts of women. Mycoplasma hominis has been associated with a number of clinically significant infections, although it is also part of the normal genital flora. Although Mycoplasma hominis may be a co-factor in bacterial vaginosis, it has otherwise not been implicated as a cause of lower tract disease.

Run Day: Daily
Reporting Day: 2 weeks

Myoglobin, Serum

Test Code: 1245 CPT Code: 83874
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: ECLIA
Special Requirements: No special precautions needed
Clinical Significance:

The breakdown of skeletal muscle (rhabdomyolysis) releases myoglobin.

Run Day: Daily
Reporting Day: Same day

Myoglobin, Urine

Test Code: 7116 CPT Code: 83874
Specimen Type: Urine in sterile leak proof container
Sample Volume: 10 mL
Transport Condition: Frozen condition
Specimen Rejection Criteria: NA
Methodology: Nephelometry
Special Requirements: No special precautions needed
Clinical Significance:

The breakdown of skeletal muscle (rhabdomyolysis) releases myoglobin. Very high concentrations of myoglobin may increase the risk of acute renal failure.

Run Day: Daily
Reporting Day: 6th day

Myomectomy, Fibroids of more than 2 cm size

Test Code: 2882 CPT Code: 88305
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day