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Pancreas, Pancreatectomy

Test Code: 1430 CPT Code: 88309
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

PAP Smear (Thin Prep Smears), Gynecological Cytology

Test Code: 1440 CPT Code: 88164
Specimen Type: Smears
Sample Volume: Smear fixed immediately with spray fixative or 95% ethyl alcohol
Transport Condition: Room temperature
Specimen Rejection Criteria: Slide broken in transit beyond ability to repair
Methodology: Conventional smears
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The conventional PAP Smear is intended for use in screening for the presence of atypical cells, cervical cancer, or its precursor lesions, as well as all other cytologic categories.

Run Day: Daily, except Fri
Reporting Day: Next day

PAP Smear, Conventional

Test Code: 6285 CPT Code: 88164
Specimen Type: Smears
Sample Volume: Smear fixed immediately with spray fixative or 95% ethyl alcohol
Transport Condition: Room temperature
Specimen Rejection Criteria: Slide broken in transit beyond ability to repair
Methodology: Conventional smears
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The conventional PAP smear is intended for use in screening for the presence of atypical cells, cervical cancer, or its precursor lesions, as well as all other cytologic categories.

Run Day: Daily, except Fri
Reporting Day: 2nd day

Papilloma virus, Human, Amplified Probe Technique Infectious Agent Detection by Nucleic acid (DNA or RNA)

Test Code: 4735 CPT Code: 87621
Specimen Type: Thin prep vial
Sample Volume: 10 mL
Transport Condition: Room temperature
Specimen Rejection Criteria: NA
Methodology: HPV Microarray
Special Requirements: No special precautions needed
Clinical Significance:

Helps in detection of high risk and low risk HPV genotypes present in the sample. Clinically important for the screening of cervical cancer.

Run Day: Sun, Wed
Reporting Day: Next day

Parathyroid Hormone (PTH), Blood

Test Code: 484 CPT Code: 83970
Specimen Type: Plasma EDTA (Whole blood in a lavender-top (EDTA) tube)
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Grosshemolysis and lipemia
Methodology: Immunoassay
Special Requirements: No special precautions needed
Clinical Significance:

The major function of PTH is to maintain the serum total calcium concentration within a narrow range. The net effects of PTH are to increase the serum concentration of calcium and to decrease that of phosphate. The assay is useful in making the diagnosis of primary hyperparathyroidism, secondary hyperparathyroidism, and in differential diagnosis of hypercalcemia. The assay helps to distinguish hypercalcemia
caused by primary hyperparathyroidism and malignant diseases.

Run Day: Sat, Mon, Wed
Reporting Day: Next day

Parathyroids, Parathyroidectomy

Test Code: 1403 CPT Code: 88305
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Parvovirus B19 Antibodies, IgG, Serum

Test Code: 13954 CPT Code: 86747
Specimen Type: Serum (yellow-top tube)
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Grosshemolysis, icteric and hyperlipemic
Methodology: Enzyme immunoassay
Special Requirements: No special precautions needed
Clinical Significance:

Parvovirus B19 preferentially replicates in erythroid progenitor cells. Infection with parvovirus B19 occurs early in life and the virus is transmitted by respiratory secretion and occasionally by blood products. Parvovirus B19 may result in an asymptomatic infection or produce a wide spectrum of human diseases, including persistent anemia especially in immunocompromised/ transplant patients, and infants. This assay is used in serologic detection of recent or past parvovirus B19 infection.

Run Day: Tue
Reporting Day: Same day

Parvovirus B19 Antibody, IgM, Serum

Test Code: 13294 CPT Code: 86747
Specimen Type: Serum (yellow-top tube)
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Grosshemolysis, icteric and hyperlipemic
Methodology: Enzyme immunoassay
Special Requirements: No special precautions needed
Clinical Significance:

Parvovirus B19 preferentially replicates in erythroid progenitor cells. Infection with parvovirus B19 occurs early in life and the virus is transmitted by respiratory secretion and occasionally by blood products. Parvovirus B19 may result in an asymptomatic infection or produce a wide spectrum of human diseases, including persistent anemia especially in immunocompromised/ transplant patients, and infants. This assay is used in serologic detection of recent or past parvovirus B19 infection.

Run Day: Tue
Reporting Day: Same day

Parvovirus B19, Molecular Detection, PCR

Test Code: 13756 CPT Code: 87798
Specimen Type: Plasma EDTA/ whole blood EDTA/ bone marrow EDTA (lavender-top tubes)
Sample Volume: 0.5 mL for each tube
Transport Condition: Refrigerated whole blood & bone marrow, frozen plasma
Specimen Rejection Criteria: Nil
Methodology: PCR
Special Requirements: Specimen source is required.
Clinical Significance:

Parvovirus B19 preferentially replicates in erythroid progenitor cells. Infection with parvovirus B19 occurs early in life and the virus is transmitted by respiratory secretion and occasionally by blood products. Parvovirus B19 may result in an asymptomatic infection or produce a wide spectrum of human diseases, including persistent anemia especially in immunocompromised/ transplant patients, and infants. This assay is used for rapid detection of parvovirus B19 DNA in blood/ bone marrow by PCR, as an aid in the diagnosis of infection by this pathogen.

Run Day: Tue
Reporting Day: 4th day

Pelvic exenteration

Test Code: 1431 CPT Code: Use individual CPTCodes
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Penis, Penectomy

Test Code: 1404 CPT Code: 88309
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Peripheral Nerve Biopsy

Test Code: 1383 CPT Code: 88305
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Phenobarbital, Serum

Test Code: 7093 CPT Code: 80184
Specimen Type: Serum collected in a red-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Serum collected in a yellow-top tube separator tube
Methodology: Immunoassay
Special Requirements: Results from specimen collected 2 to 4 hrs after dose can be misleading. Treatment history required
Clinical Significance:

Phenobarbital is a general central nervous system suppressant used in the control of generalized and partial seizures. Phenobarbital assay is useful in monitoring for appropriate therapeutic concentration of the drug and in assessing compliance or toxicity.

Run Day: Tue, Thurs
Reporting Day: Next day

Phenylalanine, Neonatal Screening

Test Code: 3620 CPT Code: 84030
Specimen Type: Dry Blood Spots
Sample Volume: 2 Dry Blood Spots
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: NA
Methodology: Enzyme immunoassay
Special Requirements: Newborn infants are screened regardless of gestational age, weight, feeding or healthstatus between 48 and 72 hours of life.
Clinical Significance:

Phenylketonuria is an inherited autosomal recessive condition caused by an enzyme deficiency (phenylalanine hydroxylase) which results in the inability
to convert phenylalanine to tyrosine. This quantitative assay determines phenylalanine levels in neonatal dried blood spot samples and is a screening test for phenylketonuria (PKU)

Run Day: Mon, Thurs
Reporting Day: Next day

Phenytoin, Serum

Test Code: 1129 CPT Code: 80185
Specimen Type: Serum collected in a red-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Room temperature
Specimen Rejection Criteria: Serum collected in a yellow-top tube separator tube
Methodology: ECLIA
Special Requirements: No special precautions needed
Clinical Significance:

Phenytoin is an anticonvulsant used for the treatment of generalized tonic-clonic
(grand mal) and complex partial seizures. Phenytoin is also used for prophylaxis in neurosurgical procedures. Phenytoin levels are monitored to assure adequate therapeutic levels are achieved and to avoid toxicity.

Run Day: Mon, Wed, Sat
Reporting Day: Next day

Philadelphia Chromosome (BCR/ ABL Gene Rearrangement), Quantitative

Test Code: 16001 CPT Code:
Specimen Type: Sodium heparin whole blood/ bone marrow
Sample Volume: 3 mL
Transport Condition: Room temperature
Specimen Rejection Criteria: Sample received in any other tube.
Methodology: Cell culture
Special Requirements: Clinical details in specified format required
Clinical Significance:

The BCR-ABL fusion gene is formed by a translocation between chromosomes 9 and 22 [t(9;22)]. The fusion gene is the hallmark diagnostic feature, being present in virtually all individuals with CML. It is also present in some adults and children with ALL. This assay aids in diagnosis of CML, identifying acute lymphoblastic leukemia (ALL) with t(9;22) BCR/ABL rearrangement (Ph+ ALL), selecting treatment inpatients with ALL, monitoring the effectiveness of therapy, monitoring minimal residual disease (MRD), and predicting disease progression.

Run Day: Sat, Wed
Reporting Day: 21st day

Phosphorus, 24 Hrs, Urine

Test Code: 16321 CPT Code: 84105
Specimen Type: 24 hrs Urine
Sample Volume: 5 mL
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: NA
Methodology: Spectrophotometry
Special Requirements: 24 hrs urine with 15 mL 6 N HCL. Refrigerate specimen within 4 hours of completion of 24-hour collection. Mention 24 hrs urine volume.
Clinical Significance:

Approximately 80% of filtered phosphorus is reabsorbed by renal proximal tubule cells. The regulation of urinary phosphorus excretion is mainly dependent on regulation of proximal tubu-lar phosphorus reabsorption. Urinary phosphorus excretion is increased by high phosphorus diet, parathyroid hormone, extracellular volume expansion, low dietary potassium intake, proximal tubule defects (eg, Fanconi syndrome, X-linked hypophosphatemic rickets, tumor-induced osteomalacia).
Factors which decrease, or are associated with decreases in, urinary phosphorus excretion include low dietary phosphorus intake, insulin, high dietary potassium intake, and decreased intestinal absorption of phosphorus (eg, phosphate-binding antacids, vitamin D deficiency, malabsorption states).

Run Day: Daily
Reporting Day: Same day

Phosphorus, Serum

Test Code: 306 CPT Code: 84100
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: Spectrophotometry
Special Requirements: No special precautions needed
Clinical Significance:

Serum phosphorus levels in isolation are of limited diagnostic value and should be correlated with serum calcium levels. An increased phosphorus with decreased calcium suggests either hypoparathyroidism or renal disease. A decreased phosphorus and an increased calcium suggests hyperparathyroidism or sarcoidosis. When both calcium and phosphorus are decreased, diagnostic considerations include malabsorption, vitamin D deficiency and renal tubular acidosis. Increased phosphorus and normal or increased calcium suggests milk-alkali syndrome or hypervitaminosis D.

Run Day: Daily
Reporting Day: Same day

Phosphorus, Urine

Test Code: 1090 CPT Code: 84105
Specimen Type: Urine in sterile leak proof container
Sample Volume: 10 mL
Transport Condition: Room temperature
Specimen Rejection Criteria: NA
Methodology: Spectrophotometry
Special Requirements: No special precautions needed
Clinical Significance:

Urinary phosphorus concentration is useful to assess calcium and phosphorus balance. Thyroid and kidneys are key organs influencing urinary excretion. Many medical conditions affect urinary phosphorus levels.

Run Day: Daily
Reporting Day: Next day

Placenta

Test Code: 1405 CPT Code: 88305,88307
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Platelet Antibody, Serum

Test Code: 8425 CPT Code: 86022
Specimen Type: Serum (yellow-top tube)
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Grosshemolysis and hyperlipemic
Methodology: Immunofluorescence
Special Requirements: Do not collect within 72 hours of a platelet transfusion as the same will interfere with this assay. Clinical history is required.
Clinical Significance:

Serum platelet antibody assay is used for detection of alloantibodies to epitopes on platelet glycoproteins IIb/IIIa, Ib/Ix, Ia/ IIa, IV and HLA Class I antigens to evaluate cases of immune mediated refractoriness to platelet transfusions, posttransfusion
purpura, or neonatal alloimmune thrombocytopenia.

Run Day: Sat
Reporting Day: 4th day

Platelets Count

Test Code: 459 CPT Code: 85049
Specimen Type: Whole blood in a lavender-top (EDTA) tube
Sample Volume: 3.0 mL (1.0mL min)
Transport Condition: Room temperature
Specimen Rejection Criteria: Grosshemolysis and clotted
Methodology: Cell counter
Special Requirements: No special precautions needed
Clinical Significance:

Platelets must be present in adequate numbers. It plays an important role in hemostasis.

Run Day: Daily
Reporting Day: Same day

Polycystic Ovary Syndrome (PCOS) Profile (FSH, LH, Prolactin, Total Testosterone, Insulin Fasting, Insulin PP, FBS)

Test Code: 6239 CPT Code: Use individual CPTCodes
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 5.0 mL
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Hemolysis/ received room temperature
Methodology: Immunoassay
Special Requirements: 10 to 12 hrs fasting is preferred for glucose and insulin fasting specimen
Clinical Significance:

See individual assays.

Run Day: Daily
Reporting Day: Next day

Porphobilinogen, 24 Hrs, Quantitative, Urine

Test Code: 1254 CPT Code: 84110
Specimen Type: 24 hrs Urine
Sample Volume: 20 mL - min
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Received room temperature. Not protected from light
Methodology: Chromatography/ Spectrophotometry
Special Requirements: 24 hours urine, without preservative. Refrigerate during collection. To protect from light, specimen should be collected in a dark coloured bottle. On TRF endorse 24 hrs total urine volume along with patient age, gender and clinical history details.
Clinical Significance:

The porphyrias are a group of inherited disorders resulting from enzyme defects in the heme biosynthetic pathway. Depending on the specific enzyme involved, various porphyrins and their precursors accumulate in different specimen types. This assay is useful for evaluation ofa suspected acute porphyria: acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria. It is
recommended that specimen is collected during the acute phase. Porphobilinogen may be normal when the patient is not exhibiting symptoms.

Run Day: Wed
Reporting Day: Next day

Porphyrins, 24 hrs, Urine, Quantitative

Test Code: 6954 CPT Code: 84120
Specimen Type: 24 hrs urine in sterile leak proof container
Sample Volume: 10 mL
Transport Condition: Room temperature
Specimen Rejection Criteria: Urine with preservative
Methodology: Chromatography/Spectrophotometry
Special Requirements: 24 hrs urine without preservative. Clinical history is mandatory. To protect from light, the urine specimen should be collected in dark colour bottle. Courier the 24 hrs urine aliquot in dark brown container. Mention 24 hrs urine volume on the requisition form.
Clinical Significance:

Porphyria is a group of disorders characterized by the abnormal accumulation of porphyrins or porphyrin precursors. Porphyrin fractionation of urine is useful in diagnosing porphyrin cutanea tarda, hereditary coproporphyria, and variegate porphyria.

Run Day: Wed
Reporting Day: 2nd day

Potassium, 24 hrs, Urine

Test Code: 3998 CPT Code: 84133
Specimen Type: 24 hrs urine in sterile leak proof container
Sample Volume: 10 mL
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: NA
Methodology: ISE
Special Requirements: 24 hrs urine without preservatives. Clinical history is mandatory. Mention 24 hrs urine volume on the requisition form.
Clinical Significance:

Assessment of hydration status and overall electrolyte balance.

Run Day: Daily
Reporting Day: Same day

Potassium, Random, Urine

Test Code: 3999 CPT Code: 84133
Specimen Type: Urine in sterile leak proof container
Sample Volume: 10 mL
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: NA
Methodology: ISE
Special Requirements: No special precautions needed
Clinical Significance:

Assessment of hydration status and overall electrolyte balance.

Run Day: Daily
Reporting Day: Same day

Potassium, Serum

Test Code: 307 CPT Code: 84132
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: ISE
Special Requirements: No special precautions needed
Clinical Significance:

Potassium measurement is useful in monitoring electrolyte balance in the diagnosis and treatment of disease conditions characterized by low or high blood potassium levels. Potassium is elevated in adrenal cortical insufficiency, acute renal failure and in some cases of diabetic acidosis. Potassium is decreased in diuretic administration and renal tubular acidosis.

Run Day: Daily
Reporting Day: Same day

Pre Eclampsia Profile (PIGF & sFlt-1)

Test Code: 7078 CPT Code: Use individual CPTCodes
Specimen Type: Serum collected in yellow-top tube
Sample Volume: 3.0 mL
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: Immunoassay
Special Requirements: No special precautions needed
Clinical Significance:

The PLGF and sFlt-1 concentrations are measured by immunoassay in maternal blood to improve the diagnostic possibilities in preeclampsia.

Run Day: Sun
Reporting Day: 3rd day

Pregnancy Test, Serum

Test Code: 1102 CPT Code: 84703
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Room temperature
Specimen Rejection Criteria: Gross hemolysis
Methodology: ECLIA
Special Requirements: No special precautions needed
Clinical Significance:

hCG may reach detectable limits within 7-10 days of conception. hCG is produced by the placenta and reaches a peak between the 7th and 10th week of gestation. hCG is a glycoprotein hormone produced by the syncytiotrophoblast of placenta and secreted during normal pregnancy and with pathologic conditions such as hydatidiform mole, choriocarcinoma and testicular neoplasm.
Order hCG, Total, QL & Urine, if hCG serum result is inconsistent with clinical presentation.

Run Day: Daily
Reporting Day: Same day

Pregnancy Test, Urine

Test Code: 1101 CPT Code: 81025
Specimen Type: Urine in sterile leak proof container
Sample Volume: 10 mL
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: NA
Methodology: ECLIA
Special Requirements: No special precautions needed
Clinical Significance:

This test is specific for HCG beta sub unit and offers sensitivity necessary to detect pregnancy as early as ten days post conception.

Run Day: Daily
Reporting Day: Same day

Prenatal Testing by Fluorescence In Situ Hybridization (FISH)

Test Code: 13192 CPT Code: 88271
Specimen Type: Cord blood in Sodium heparin tube (green- top), amniotic fluid
Sample Volume: Blood: 3-5 mL, Amniotic fluid-10mL in sterile centrifuge tube with consent form
Transport Condition: Room temperature
Specimen Rejection Criteria: Frozen
Methodology: FISH (Fluorescence in situ hybridization)
Special Requirements: Clinical history and informed consent is essential
Clinical Significance:

Approximately half of clinically recognizable spontaneous abortions have a major chromosomal anomaly, out of which up to 95% involve aneuploidy (gain or loss of whole chromosome) of chromosomes 13, 18, 21, X, and
Y. FISH, which uses DNA probes, can rapidly detect aneuploidy of
13, 18, 21, X and Y.

Run Day: Daily
Reporting Day: 7 days

Procalcitonin Test (PCT-Q)

Test Code: 3646 CPT Code: 84145
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: ECLIA
Special Requirements: Clinical history is essential.
Clinical Significance:

Procalcitonin (ProCT) assay is useful in diagnosis of bacteremia & septicemia in adults and children including neonates. It diagnoses renal involvement in UTI in children, bacterial infection in neutropenic patients & secondary infection post surgery. It helps in the differential diagnosis of bacterial versus viral meningitis and community acquired bacterial versus viral pneumonia. ProCT becomes detectable within 2 to
4 hours after a triggering event and peaks by 12 to 24 hours. ProCT secretion parallels closely the severity of the inflammatory insult, with higher levels associated with more severe disease and declining levels with resolution of illness. In the absence of an ongoing stimulus, ProCT is eliminated with a half-life of 24 to 35 hours, making it suitable for serial monitoring.

Run Day: Daily
Reporting Day: 3rd day

Progesterone, Serum

Test Code: 485 CPT Code: 84144
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: ECLIA
Special Requirements: Clinical history and timing of specimen collection is essential
Clinical Significance:

Levels increases sharply during the luteal phase of the menstrual cycle. The level also increases from 9 to 32 weeks of pregnancy.

Run Day: Daily
Reporting Day: Same day

Prolactin, Serum

Test Code: 486 CPT Code: 84146
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Gross hemolysis, icteric and lipemic
Methodology: ECLIA
Special Requirements: Clinical history and timing of Specimen collection is essential
Clinical Significance:

Prolactin is a single-chain polypeptide hormone secreted by the anterior pituitary under the control of prolaction-releasing factors. These inhibiting and releasing factors
are secreted by the hypothalamus. Prolactin is also synthesized by the placenta and is present in amniotic fluid. It initiates and maintains lactation in females and also plays a role in regulating gonadal function in both males and females. In adults, basal circulating prolactin is present in concentratins up
to 30 ng/mL. During pregnancy and postpartum lactation, serum prolactin can increase 1to 20fold. Exercise, stress, and sleep also cause transient increase in prolactin levels. Consistently elevated serum prolactin levels greater then 30 ng/mL, in the absence of pregnancy and postpartum lactation, are indicative of hyperprolactinemia, which is the most common hypothalamic-pituitary dysfunction. Hyperprolactinemia often results in galactorrhea, amenorrhea, and infertility in females, and in impotence and hypogonadism in males. Renal failure, hypothyroidism, and prolactin-secreting pituitary adenomas are also common causes of abnormally elevated prolactin levels.

Run Day: Daily
Reporting Day: Same day

Prostate Specific Antigen (PSA), Free

Test Code: 1264 CPT Code: 84154
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: ECLIA
Special Requirements: Direct Rectal Examination (DRE), prostatic biopsy or ejaculation prior to test should be avoided
Clinical Significance:

In men over age 50 years with total PSA between 4.0 and 10.0 ng/mL, those with prostate cancer tend to have lower % free PSA than those with benign prostatic hypertrophy (BPH), although there is considerable overlap in results for the two populations. % free PSA may aid in avoiding unnecessary biopsies in these circumstances.

Run Day: Daily
Reporting Day: Same day

Prostate Specific Antigen (PSA), Total

Test Code: 1152 CPT Code: 84153
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: ECLIA
Special Requirements: Direct Rectal Examination (DRE), prostatic biopsy or ejaculation prior to test should be avoided
Clinical Significance:

Elevate serum PSA concentration have been reported in men with prostate cancer, benign prostatic hypertrophy, and inflammatory conditions of the prostate.

Run Day: Daily
Reporting Day: Same day

Prostate, Needle Biopsy

Test Code: 1363 CPT Code: 88305
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Prostate, Radical Prostatectomy for Tumor

Test Code: 1432 CPT Code: 88309
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Prostate, Suprapubic Prostatectomy for Nodular Hyperplasia

Test Code: 1406 CPT Code: 88307
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Prostate, Transurethral Resection (TURP)

Test Code: 1384 CPT Code: 88305
Specimen Type: Tissue
Sample Volume: Specimen in 10% buffered formalin
Transport Condition: Room temperature
Specimen Rejection Criteria: Received frozen
Methodology: Microscopy
Special Requirements: Clinical history and sample site are essential
Clinical Significance:

The nature of possible underlying disease can be ruled out/confirmed through histopathological examination

Run Day: Daily, except Fri
Reporting Day: 4th day

Protective Antibodies Panel (Anti Hbs, Varicella IgG & IgM, Rubella IgG & IgM, Mumps IgG & IgM, Measles IgG & IgM Antibodies)

Test Code: 6911 CPT Code: Use individual CPTCodes
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: serum,3.0 mL
Transport Condition: Refrigerated condition/ frozen condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: Immunoassay
Special Requirements: No special precautions needed
Clinical Significance:

Protective antibody titers for a range of infectious diseases.

Run Day: Sat, Tue, Thurs
Reporting Day: Same day

Protein C Activity

Test Code: 6906 CPT Code: 85303
Specimen Type: Citrated plasma [Whole blood in blue-top (sodium citrate) tube]
Sample Volume: 2.0 mL
Transport Condition: Frozen condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: Clot Detection
Special Requirements: No special precautions needed
Clinical Significance:

Comprehensive test assesses the total level of protein and its functional activity in determiningprotein C deficiency, which is strongly prothrombotic, and may require long term anticoagulation therapy. In the presence of low protein C Activity, protein
C antigen helps to confirm and to classify protein C deficiency as type I or type II. Protein C is a highly thrombophilic protein.

Run Day: Wed
Reporting Day: Next day

Protein Electrophoresis

Test Code: 1255 CPT Code: 84165
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: Electrophoresis
Special Requirements: No special precautions needed
Clinical Significance:

Protein electrophoresis evaluates the major protein fractions to determine if there are deficiencies or excesses as seen with macroglobulinemia and multiple myeloma. Immunofixation is useful in characterizing M components.

Run Day: Mon, Thurs
Reporting Day: Next day

Protein Electrophoresis, CSF

Test Code: 15686 CPT Code: 84166
Specimen Type: CSF
Sample Volume: 3.0 mL (2.0mL - min)
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Nil
Methodology: Electrophoresis
Special Requirements: Clinical history is required
Clinical Significance:

CSF protein electrophoresis is useful in identifying oligoclonal band, and other protein variations that are associated with multiple sclerosis and occasionally, viral illnesses.

Run Day: Daily
Reporting Day: 3rd day

Protein Electrophoresis, Urine

Test Code: 16394 CPT Code: 84166
Specimen Type: 24 hrs urine
Sample Volume: 15 mL
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Nil
Methodology: Electrophoresis
Special Requirements: Refrigerate specimen during collection and send refrigerated.
Clinical Significance:

Urine proteins can be grouped into 5 fractions by protein electrophoresis: Albumin, Alpha-1, Alpha-2, Beta-globulin and Gamma globulin. The electrophoretic pattern and the presence of a monoclonal immunoglobulin light chain may be characteristic of monoclonal gammopathies such as multiple myeloma, primary systemic amyloidosis, and light-chain deposition disease.

Run Day: Mon, Thurs
Reporting Day: Same day

Protein S, Free

Test Code: 6907 CPT Code: 85306
Specimen Type: Citrated plasma [Whole blood in blue-top (sodium citrate) tube]
Sample Volume: 3.0 mL
Transport Condition: Frozen condition
Specimen Rejection Criteria: Hemolysis
Methodology: Clot Detection
Special Requirements: No special precautions needed
Clinical Significance:

This test is often useful in the comprehensive evaluation of protein S when deficiency is suspected, allowing forassessment of the free protein S, separate from total protein S, which includes C4BP. The clinical use of this test is important in the evaluation of physiologically
available protein S in patients with lupus anticoagulant, and in the further classification of
protein S deficiency. Protein S is a highly thrombophilic protein.

Run Day: Wed
Reporting Day: Next day

Protein S, Total

Test Code: 1227 CPT Code: 85305
Specimen Type: Citrated plasma [Whole blood in blue-top (sodium citrate) tube]
Sample Volume: 3.0 mL
Transport Condition: Frozen condition
Specimen Rejection Criteria: Hemolysis
Methodology: Clot Detection
Special Requirements: No special precautions needed
Clinical Significance:

For investigation of coagulation disorders

Run Day: Wed
Reporting Day: Next day

Protein, 24 Hrs, Urine

Test Code: 4001 CPT Code: 84156
Specimen Type: Urine in sterile leak proof container
Sample Volume: 10 mL
Transport Condition: Room temperature
Specimen Rejection Criteria: Acidified urine
Methodology: Spectrophotometry
Special Requirements: 24 hrs urine (with 6N HCL as preservative). Clinical history is required. Mention 24 hrs urine volume on the requisition form.
Clinical Significance:

Proteinuria, mainly glomerular, is often a manifestation of primary renal disease although transient proteinuria may occur with fevers, thyroid disorders, and in heart diseases. In the absence of renal disease, the degree of proteinuria is slight, usually amounting to less than 2 grams per day.In chronic glomerulonephritis and in the nephrotic syndrome, including lipoid nephrosis, and in some forms of hypertensive vascular diseases, protein loss may vary from a few grams to as much as 30 g/day.

Run Day: Daily
Reporting Day: Same day

Prothrombin Time with INR

Test Code: 456 CPT Code: 85610
Specimen Type: Citrated plasma [Whole blood in blue-top (sodium citrate) tube]
Sample Volume: 2.0 mL , upto the mark intube
Transport Condition: Refrigerated condition
Specimen Rejection Criteria: Hemolysis
Methodology: Clotting
Special Requirements: No special precautions needed
Clinical Significance:

Bleeding disorder may be due to inherited or acquired deficiencies of a clotting factor

Run Day: Daily
Reporting Day: Same day

Pseudo Cholinesterase, Serum

Test Code: 1238 CPT Code: 82480
Specimen Type: Serum collected in a yellow-top tube
Sample Volume: 3.0 mL (1.0mL - min)
Transport Condition: Refrigerated/ frozen condition
Specimen Rejection Criteria: Gross hemolysis
Methodology: Spectrophotometry
Special Requirements: No special precautions needed
Clinical Significance:

The organophosphorous-containing insecticides are potent inhibitors of the true red cell cholinesterase and can cause depression of the serum pseudocholinesterase. Succinylcholine is hydrolyzed by pseudocholinesterase which, therefore influences its physiological effect. Total serum pesudocholinesterase values are decreased in patients with liver disease.

Run Day: Daily
Reporting Day: 5th day

PTH, Intact; including Calcium, Total

Test Code: 9998 CPT Code: 83970,82310
Specimen Type: Plasma EDTA [lavender-top (EDTA) tube] for I PTH; Serum (yellow-top tube) for calcium
Sample Volume: 3.0 mL (1.0 mL - min) in each tube
Transport Condition: Frozen condition
Specimen Rejection Criteria: Grosshemolysis and lipemia
Methodology: Chemiluminescence
Special Requirements: 12 hours before this test do not take multivitamins or dietary supplements containing biotin or vitamin B7
Clinical Significance:

The major function of PTH is to maintain the serum total calcium concentration within a narrow range. The net effects of PTH are to increase the serum concentration of calcium and to decrease that of phosphate. The assay is useful in making the diagnosis of primary hyperparathyroidism, secondary hyperparathyroidism, and in differential diagnosis of hypercalcemia. The assay helps to distinguish hypercalcemia
caused by primary hyperparathyroidism and malignant diseases.

Run Day: Sun
Reporting Day: Same day